Abstract: This study analyzed the quality characteristics of wrapper tobacco leaves and their associated soil chemical properties in the growing areas of Danzhou, Changjiang, Baisha, Dongfang, and Wuzhishan in Hainan, while conducting a correlation analysis to evaluate their relationships. The results indicated that: 1) The weighted score for the appearance quality of cigar wrapper tobacco leaves in Wuzhishan was the highest, while Danzhou, Changjiang, and Baisha scored significantly lower than Wuzhishan in leaf uniformity, integrity, and maturity, respectively. The leaf thickness and leaf mass per unit area in Wuzhishan were significantly higher than those in Changjiang and Baisha. The stem content of leaves in Baisha was the highest, and the tensile strength of leaves in Changjiang was the highest. There were differences in the contents of mineral elements such as chlorine, sulfur, potassium, calcium, and magnesium in tobacco leaves among different growing areas. The sensory quality of tobacco leaves varied greatly among different growing areas, with Baisha and Wuzhishan achieving significantly higher total scores than the other growing areas. 2) In Hainan tobacco growing areas, the soil was weakly acidic. There were significant differences in soil chemical properties among different growing areas. Wuzhishan exhibits the most abundant soil nutrients overall, along with the highest organic matter content. In contrast, the cation exchange capacity in Danzhou soil and the organic matter contents in Changjiang soil were the lowest, while the available chlorine content in Dongfang soil was the highest. 3) The body, branch vein condition, and leaf structure of tobacco leaves were significantly or extremely significantly negative correlated with soil chemical properties. The total appearance score was significantly positively correlated with soil total phosphorus content and extremely significantly positively correlated with soil exchangeable calcium. The physical characteristics of tobacco leaves were significantly correlated with the contents of soil available potassium and effective boron, while soil organic matter content significantly affects the sugar content of tobacco leaves. Additionally, chlorine content of tobacco leaves was significantly positively correlated with soil available chlorine and available phosphorus. Furthermore, leaf maturity, cleanliness, and sweetness were significantly positively correlated with soil total phosphorus content. Therefore, to produce high-quality wrapper tobacco in Hainan, region-specific management strategies and rational regulation of soil nutrients should be implemented to enhance leaf quality.