Abstract: In order to study the relationship between meteorological factors and growth, yield and quality of tobacco, and to clarify the limiting meteorological factors for tobacco leaf production and optimize the allocation of climate resources in Shandong, a series of experiments with different transplanting date treatments using main varieties including NC55, NC102 and ZY100 were conducted in multiple years. The results showed that transplanting date had certain influence on the agronomic and economic traits of tobacco and had significant effects on tobacco leaf quality. As the transplanting date being delayed, the leaf width in some experiments increased, the yield and output value of some experiments increased first and decreased afterwards, the total plant alkali content decreased significantly, the content of reducing sugar and total sugar, and the ratio of sugar to alkali increased, the quality sensory evaluation of tobacco leaves increased first and then decreased. The order of correlation between meteorological factors and tobacco leaf quality was daily average temperature > average sunshine hours > average precipitation. Regression equations for quality assessment of Shandong tobacco based on average temperature were constructed, and the temperature conditions required for the production of high-quality tobacco leaves for each variety were calculated, the results of which indicated that the suitable average temperature for NC55, NC102 and ZY100 were 21.25-22.86℃, 21.53-22.68℃ and 20.81-23.22℃ during root spreading period, 23.67-24.54℃, 24.32-24.83℃ and 22.03-24.42℃ during late maturity period, respectively, and the inferred suitable transplanting dates for the three varieties was May 5 to 19, May 7 to 16 and May 1 to 25, respectively.