Abstract: In order to determine the effects of field management practices on tobacco growing soil nutrients in Zunyi tobacco area in the past 10 years, taking the central area of Zunyi as an example, the method of inverse distance weight in ArcGIS was employed to analyse the changes of soil organic matter, total nitrogen, alkali hydrolyzed nitrogen, available phosphorus, slow-release potassium, available potassium and pH in 2006 and 2016 in Bozhou, Huichuan District and Xinpu New District of Zunyi, respectively. Results showed that the variation of nutrient contents in Zunyi tobacco growing soils was distinct. The contents of slow-release potassium and available potassium increased by 36.43% and 57.25%, respectively, while the contents of organic matter, total nitrogen, alkali hydrolyzed nitrogen, available phosphorus and pH decreased by 23.17%, 18.62%, 16.78%, 49.88% and 0.52, respectively. In terms of spatial distribution, the contents of soil organic matter, total nitrogen, available nitrogen and available phosphorus mainly exhibited decreasing trend, accounting for 87.2%, 81.1%, 90%, 93.5% and 80.0% of the total area, respectively, whereas the contents of slow-release potassium and available potassium exhibited increasing trend, accounting for 84.2% and 90.2% of the total area, respectively. The variations of nutrient spatial distribution indicates that the application of field fertilization and management practices is standardized, and its effect on tobacco growing soil in Zunyi tobacco area exhibits identity. The variation of different nutrient contents proved higher application level of organic and phosphorus, maintenance of the current level of total nitrogen, and lower rates of inorganic nitrogen and potassium applied, meanwhile rational formula fertilization should be performed according to local situations.