Abstract: The relationship between main chemical components and neutral aroma components in flue-cured tobacco were studied by the method of random sampling in Yanbian. The results revealed that reducing sugars and nicotine had no significant correlation with all kinds of aromatic matter; total nitrogen had significantly or high significantly positive correlation with phenylalanine, browing reaction, neophytadiene and total amount of aroma compounds, and existed significantly positive quadratic correlation with phenylalanine, browing reaction contents. Protein had significantly or high significantly positive correlation with the others and total amount of aroma compounds except for cembratriendid, and had significant or high significant quadratic correlations with five groups on aroma components and total amount of aroma compounds. Potassium had high significantly positive correlation with carotenoid and cembratriendid, and assumed significant or very significant quadratic correlations. In the range of total nitrogen contents from 1.06% to 1.99%, protein contents from 3.45% to 10.18%, potassium contents from 0.66% to 1.94%, if increasing their contents, the content of aroma matters increased.