Abstract: High population with limited land, tobacco competing land with grain crop, difficult in adjusting tobacco planting system, continuous tobacco planting, severe soil compaction, increasing diseases and insects, all of these problems influenced tobacco production in Linqu county. Based on long-term experiments and demonstration, the advantage of flue-cured tobacco and sweet potato intercopping system, planting mode, economic profit, and the key measures for extension were analyzed. The results indicated that flue-cured tobacco and sweet potato inter-cropping system could increase profit per unit land area and tobacco planting area. The system is an effective adjustment measure under the condition of difficult in adjusting rotation in large scale.